Effect of EGCG on cisplatin-induced nitrative stress in mice.

<p>Panel A. Histological examination revealed significant protein nitration in the renal tubules of the cisplatin-treated group. EGCG treatment reduced the level of protein nitration similar to vehicle level. Panel B. Quantitative measurement of 3-nitrotyrosine adducts in protein also demonstrated similar trend. Results are mean ± S.E.M. n = 4/group.* p<0.05 versus vehicle; and # p<0.05 versus cisplatin.