<p>Cisplatin administration resulted in severe tubular damage as shown by histological examination using PAS staining. The damage was attenuated by EGCG treatment at dose 100mg/kg (designated as EGCG 100). Results are mean ± S.E.M., n = 4/group.* p<0.05 versus vehicle; and # p<0.05 versus cisplatin.</p
Background: Cisplatin is a potent chemotherapeutic drug for cancer therapy, but it has serious side ...
Cisplatin (CDDP) is a first-choice therapy for many cancers, but 30% of patients develop acute kidne...
<p>Cisplatin-induced renal dysfunction was measured by the levels of BUN and creatinine. A. BUN and ...
<p>Cisplatin caused significant renal dysfunction as measured by the levels of creatinine (Panel A) ...
<p>Panel A. Histological examination revealed significant protein nitration in the renal tubules of ...
<p>Panel A. Immuno-blot analyses of nuclear fraction from kidney demonstrated increase in p65 in cis...
<p>C57BL/6 mice (males, n = 8 mice per group) were injected daily for 4 days, prior to cisplatin (20...
<p>Histological examination (Panel A) and quantification (Panel B) revealed necrosis, protein cast, ...
<p>EGCG inhibit cisplatin induced mitochondrial ROS (Reactive Oxygen Species) in the renal tubular c...
<p>Real-time PCR based analyses of pro-inflammatory cytokines TNFα and IL1β indicated profound incre...
<p>Cisplatin reduced the enzyme activities of mitochondrial electron transport chain namely (Panel A...
<p>Hematoxylin and eosin (H&E) staining revealed the presence of tubular casts and obstructions (arr...
<p>Kidney tissue sections from control (A) and baicalein alone (B) treated mice showing normal kidne...
<p>(A) Serum BUN and creatinine (Cr) in wild-type and RAMP2+/−3 days after administration of vehicle...
Since cisplatin-induced nephrotoxicity has very important clinical consequences, purpose of this stu...
Background: Cisplatin is a potent chemotherapeutic drug for cancer therapy, but it has serious side ...
Cisplatin (CDDP) is a first-choice therapy for many cancers, but 30% of patients develop acute kidne...
<p>Cisplatin-induced renal dysfunction was measured by the levels of BUN and creatinine. A. BUN and ...
<p>Cisplatin caused significant renal dysfunction as measured by the levels of creatinine (Panel A) ...
<p>Panel A. Histological examination revealed significant protein nitration in the renal tubules of ...
<p>Panel A. Immuno-blot analyses of nuclear fraction from kidney demonstrated increase in p65 in cis...
<p>C57BL/6 mice (males, n = 8 mice per group) were injected daily for 4 days, prior to cisplatin (20...
<p>Histological examination (Panel A) and quantification (Panel B) revealed necrosis, protein cast, ...
<p>EGCG inhibit cisplatin induced mitochondrial ROS (Reactive Oxygen Species) in the renal tubular c...
<p>Real-time PCR based analyses of pro-inflammatory cytokines TNFα and IL1β indicated profound incre...
<p>Cisplatin reduced the enzyme activities of mitochondrial electron transport chain namely (Panel A...
<p>Hematoxylin and eosin (H&E) staining revealed the presence of tubular casts and obstructions (arr...
<p>Kidney tissue sections from control (A) and baicalein alone (B) treated mice showing normal kidne...
<p>(A) Serum BUN and creatinine (Cr) in wild-type and RAMP2+/−3 days after administration of vehicle...
Since cisplatin-induced nephrotoxicity has very important clinical consequences, purpose of this stu...
Background: Cisplatin is a potent chemotherapeutic drug for cancer therapy, but it has serious side ...
Cisplatin (CDDP) is a first-choice therapy for many cancers, but 30% of patients develop acute kidne...
<p>Cisplatin-induced renal dysfunction was measured by the levels of BUN and creatinine. A. BUN and ...