Inhibitory effect of Gal-9 on cytokine release in co-cultures of autologous moDCs with PBLs from patients with AITD and healthy controls.

<p>PBLs were co-cultured with autologous moDCs preloaded with the superantigen SEE (0,5μg/ml), in the presence or absence of 10μg/ml hGal-9 and 50 mM lactose (Lact), as stated in Materials and Methods. Then, the concentrations of the indicated cytokines in cell culture supernatants were determined by bead-based immunoassay and analysed by flow cytometry. C, healthy controls; GD, Graves’ disease.*p<0.05, **p<0.01, ***p<0.001.