CKD risk for each additional cumulative month of NSAIDs exposure, based on DDD, (as a class or individual compound), anytime and within one year prior to the index date.

<p>NSAID = non-steroidal anti-inflammatory drug; ID = index date; OR = odds ratio.</p><p>^a Adjusted for malignant neoplasm, ischemic heart disease, diabetes mellitus, liver disease, gout, dyslipidemia, hypertension, cerebrovascular disease, lupus erythematosus systemic (LES), amyloidosis, vasculitis, myeloma, polycystic kidney, and nephrotoxic drugs (other than NSAIDs).</p><p>CKD risk for each additional cumulative month of NSAIDs exposure, based on DDD, (as a class or individual compound), anytime and within one year prior to the index date.