Anti-tumor effects of 5-FU in mice carrying TFTS66 cell xenografts.

<p>^a Tegafur, an oral prodrug of 5-FU, was administered as a combined formulation with CDHP and oxonate. 5-FU doses are expressed as those of tegafur.</p><p>^b Difference to the control, group A, was examined by Dunnett's test.</p><p>^c Difference between two 5-FU-administered groups (group E vs. C and F vs. D) was examined by Student's t-test.</p><p>^d Tumor growth inhibition (TGI) was calculated according to the following formula: TGI [%] = [(mean tumor weight (TW) of the control group)—(mean TW of the treated group)] / (mean TW of the control group) × 100.</p><p>^e Body weight change (BWC) on day 15 were calculated according to the following formula: BWC [%] = [(BW on day 15)—(BW on day 0)] / (BW on day 0) × 100.</p><p>Anti-tumor effects of 5-FU in mice carrying TFTS66 cell xenografts.