Simulated synchronized neuron.

<p>a. Classification of neuron-type [non-sync (o), sync (x), mixed (+), atypical (square)] across two parameters (Excitatory input and I/E ratio), with a fixed I-E delay of 5 ms. The two arrows indicate the parameters used for the simulated neurons in Fig. 4c (left arrow) and Fig. 4d (right arrow). b. Dependence of Rayleigh statistic (at an IPI of 75 ms) on the amplitude of excitatory inputs in simulated synchronized neurons. Spearman correlation coefficient: r = 0.99, P<3.1x10^-87. c-e. Examples of simulated and real <i>synchronized</i> neurons. Each plot is subdivided into a raster plot (left), IPI vs discharge rate plot (top right), and IPI vs vector strength plot (bottom right). The stimulus is played for 500 ms, which is indicated with the gray rectangle in the raster plot. The dashed line in the IPI vs discharge rate plot indicates a significant evoked response above the spontaneous rate (2σ). Error bars indicate SEM. c. Simulated neuron: I-E delay = 5 ms, E strength = 1.8 nS, I/E ratio = 2. d. Simulated neuron: I-E delay = 5 ms, E strength = 6 nS, I/E ratio = 2. e. Real neuron (unit m2p31.1) from awake marmoset auditory cortex.