Studies examining the long-term effects of prophylactic progesterone exposure <i>in utero</i> on childhood outcomes.

<p>PTB = preterm birth. 17 α -OHPC = 17 α -hydroxyprogesterone caproate. RR = relative risk (95% confidence interval). OR = odds ratio (95% confidence interval).</p><p>ASQ = Ages and Stages Questionnaire. PAI = Preschool Activities Inventory. CDI = Child Development Inventory. HUI = Health Utilities Index.</p><p>^#Delivery <35 weeks’ gestation.</p><p>*In the PREDICT study, follow-up was achieved for 79.2% of twins at 6 months of age and 74.8% of twins at 18 months of age.</p><p>**In our study, follow-up was achieved for 97% of twins via record linkage of at least one health record and 44% of twins via parental questionnaire.</p><p>Studies examining the long-term effects of prophylactic progesterone exposure <i>in utero</i> on childhood outcomes.