<p>Significant p-values are highlighted in bold. MAGMA p-values compared against a Bonferroni-corrected threshold of 0.05/1320 = 0.000038. For INRICH, corrected p-values (not shown) are compared against a threshold of 0.05; corrected p-value for all three significant gene-sets is 0.049.</p><p><sup>a</sup> p-values were not computed because fewer than two genes in the set overlapped with an associated interval; p-values are therefore effectively equal to 1</p><p>Competitive gene-set p-values for MAGMA and INRICH significant gene-sets.</p
<p>Genes are sorted in ascending order of interaction p-value within outcome-exposure strata.</p>a<p...
<p>We grouped the genes into bins (200 genes in each bin) according to their (A) cPI and (B) nPI val...
<p>n: number of samples; [Ct]: cycle threshold; Geo Mean [Ct]: geometric mean of Ct value; ar Mean [...
<p>Gene set -log10 p-values from the CD data competitive gene-set analysis for MAGMA, ALIGATOR, INRI...
<p>The FWER column corresponds to p-values below 0.05 after family-wise error correction, using Bonf...
<p>Comparison of gene set -log10 p-values from the CD data competitive gene-set analysis at differen...
<p>Gene set—log10 p-values from the CD data self-contained gene-set analysis for MAGMA and PLINK. Pa...
<p>Gene -log10 p-values from the CD data gene analysis in MAGMA for three different gene test-statis...
<p>Top 10 gene groups ranked by hypergeometric p-value (Bonferroni corrected for 28 tests).</p
<p>Computed p-values of highest ranked genes required to make the entire set of <i>K</i> genes signi...
(A) P-value after removal of most significant gene for pathways demonstrating p −12 across each of t...
<p>Numbers reflect total number of genes as well as the number up- and down-regulated. These numbers...
<p>A. Volcano plot for FL vs. NLN comparison. -log<sub>10</sub> p-value is plotted against the fold ...
<p>The figure shows an overlap between the genes implicated in six GWA analyses (rows) and genes rel...
<p>(ES = Enrichment Score, NES = Normalized Enrichment Score, p-val = unadjusted p-value, FWER = Fam...
<p>Genes are sorted in ascending order of interaction p-value within outcome-exposure strata.</p>a<p...
<p>We grouped the genes into bins (200 genes in each bin) according to their (A) cPI and (B) nPI val...
<p>n: number of samples; [Ct]: cycle threshold; Geo Mean [Ct]: geometric mean of Ct value; ar Mean [...
<p>Gene set -log10 p-values from the CD data competitive gene-set analysis for MAGMA, ALIGATOR, INRI...
<p>The FWER column corresponds to p-values below 0.05 after family-wise error correction, using Bonf...
<p>Comparison of gene set -log10 p-values from the CD data competitive gene-set analysis at differen...
<p>Gene set—log10 p-values from the CD data self-contained gene-set analysis for MAGMA and PLINK. Pa...
<p>Gene -log10 p-values from the CD data gene analysis in MAGMA for three different gene test-statis...
<p>Top 10 gene groups ranked by hypergeometric p-value (Bonferroni corrected for 28 tests).</p
<p>Computed p-values of highest ranked genes required to make the entire set of <i>K</i> genes signi...
(A) P-value after removal of most significant gene for pathways demonstrating p −12 across each of t...
<p>Numbers reflect total number of genes as well as the number up- and down-regulated. These numbers...
<p>A. Volcano plot for FL vs. NLN comparison. -log<sub>10</sub> p-value is plotted against the fold ...
<p>The figure shows an overlap between the genes implicated in six GWA analyses (rows) and genes rel...
<p>(ES = Enrichment Score, NES = Normalized Enrichment Score, p-val = unadjusted p-value, FWER = Fam...
<p>Genes are sorted in ascending order of interaction p-value within outcome-exposure strata.</p>a<p...
<p>We grouped the genes into bins (200 genes in each bin) according to their (A) cPI and (B) nPI val...
<p>n: number of samples; [Ct]: cycle threshold; Geo Mean [Ct]: geometric mean of Ct value; ar Mean [...