<p><sup>a, b</sup>SS, highly sensitive, survival <10<sup>-6</sup>; S, sensitive, survival comprised between 10<sup>-6</sup> and 10<sup>-4</sup>; s, slightly sensitive, survival comprised between 10<sup>-4</sup> and 10<sup>-2</sup>; R, resistant, survival >10<sup>-2</sup>.</p><p><sup>a</sup> onto TGY plates supplemented with 40 ng/mL mitomycin C (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124358#sec009" target="_blank">Materials and Methods</a>).</p><p><sup>b</sup> onto TGY plates exposed to 600 J m<sup>-2</sup> UV-rays (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0124358#sec009" target="_blank">Materials and Methods</a>).</p><p><sup>c</sup> by using the disc inhibition assay as d...
Genomic instability is considered a hallmark of carcinogenesis, and dysfunction of DNA repair and ce...
The study of spontaneous and radiation-induced mutations is at present our best approach to the inve...
Somatic mutation/Heavy ion beam/Cell cycle/LET/Hprt. To study mechanisms which could be involved in ...
<div><p>Elucidating the genetic determinants of radiation response is crucial to optimizing and indi...
o analyze ionizing radiation resistance mechanism in S. cerevisiae, we > screened gamma-ray sensitiv...
<div><p>Here, we have developed an extremely efficient <i>in vivo</i> Tn5-based mutagenesis procedur...
Elucidating the genetic determinants of radiation response is crucial to optimizing and indi-viduali...
A large number of genes are known to be responsive to ionizing radiation, and there is strong eviden...
Radiotherapy can cause unacceptable levels of damage to normal tissues in some cancer patients. To u...
The availability of a genome-wide set of Saccharomyces deletion mutants provides a chance to identif...
<p>For every gene, the z-scored LFQ intensities are compared between the control and UVC/vacuum cond...
SummaryIonizing radiation is extremely harmful for human cells, and DNA double-strand breaks (DSBs) ...
Human cells cultured in vitro are substantially different from each other in their radiosensitivity....
Ionizing radiation is extremely harmful for human cells, and DNA double-strand breaks (DSBs) are con...
<p>(A–C) <i>Smc6, MAGE</i> or <i>Smc5</i> homozygous, trans-heterozygous or hemizygous mutants have ...
Genomic instability is considered a hallmark of carcinogenesis, and dysfunction of DNA repair and ce...
The study of spontaneous and radiation-induced mutations is at present our best approach to the inve...
Somatic mutation/Heavy ion beam/Cell cycle/LET/Hprt. To study mechanisms which could be involved in ...
<div><p>Elucidating the genetic determinants of radiation response is crucial to optimizing and indi...
o analyze ionizing radiation resistance mechanism in S. cerevisiae, we > screened gamma-ray sensitiv...
<div><p>Here, we have developed an extremely efficient <i>in vivo</i> Tn5-based mutagenesis procedur...
Elucidating the genetic determinants of radiation response is crucial to optimizing and indi-viduali...
A large number of genes are known to be responsive to ionizing radiation, and there is strong eviden...
Radiotherapy can cause unacceptable levels of damage to normal tissues in some cancer patients. To u...
The availability of a genome-wide set of Saccharomyces deletion mutants provides a chance to identif...
<p>For every gene, the z-scored LFQ intensities are compared between the control and UVC/vacuum cond...
SummaryIonizing radiation is extremely harmful for human cells, and DNA double-strand breaks (DSBs) ...
Human cells cultured in vitro are substantially different from each other in their radiosensitivity....
Ionizing radiation is extremely harmful for human cells, and DNA double-strand breaks (DSBs) are con...
<p>(A–C) <i>Smc6, MAGE</i> or <i>Smc5</i> homozygous, trans-heterozygous or hemizygous mutants have ...
Genomic instability is considered a hallmark of carcinogenesis, and dysfunction of DNA repair and ce...
The study of spontaneous and radiation-induced mutations is at present our best approach to the inve...
Somatic mutation/Heavy ion beam/Cell cycle/LET/Hprt. To study mechanisms which could be involved in ...