Laboratory finding of patients with sepsis, healthy controls and patients with rheumatic disease.

<p>Patients with sepsis (n = 15) are presented with black, healthy controls (n = 8) before inflammatory stimulus by exercise with white open bars and after stimulus with white striped bars and patients with rheumatic disease (n = 23) before treatment with an anti-TNF agent with grey open bars and after treatment with grey striped bars. (A) Plasma-NGAL levels, (B) plasma creatinine levels (Crea), (C) estimated glomerular filtration rate (eGFR-EPI), (D) leukocyte count in whole blood, (E) plasma interleukin 6 levels (IL-6), (F) plasma interleukin 8 levels (IL-8), (G) plasma interleukin 10 levels (IL-10) and (H) plasma levels of C-reactive protein (CRP) are presented. * <i>P</i><0.05, ** <i>P</i><0.01, *** <i>P</i><0.001 compared to sepsis or indicated by clamp to corresponding group. Cytokine detection limits were 2.5 pg/ml for IL-6, 3.6 pg/ml for IL-8 and 3.3 pg/ml for IL-10. Bars and error bars represent median values and interquartile range.