<p>Abbrevations: CML = chronic myeloid leukemia, CP = chronic phase, AP = accelerated phase, BC = blast crisis; ET = essential thrombocythemia; PV = polycythemia vera; HES = hypereosinophilic syndrome; MF = myelofibrosis, ALL = acute lymphoblastic leukemia, bm = bone marrow; pb = peripheral blood. If JAK2V617F positive, the allele burden of the c.1849G>T mutation (which leads to V617F) detected by NGS is shown in percent of total JAK2 sequences</p><p>Patient characteristics.</p
TO THE EDITOR Several groups have recently reported the presence of a unique gain-of-function JAK2 p...
The aim of this study was to investigate the presence of Janus kinase 2 (JAK2) V617F mutation in pat...
Objective: The JAK2V617F mutation is present in the majority of patients with essential thrombocyth...
<p>ALL: acute lymphatic leukemia; AML: acute myeloid leukemia; sAML: secondary AML; CLL; chronic lym...
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy characterized by myelopr...
Since low JAK2V617F allele burden (AB) has been detected also in healthy subjects, its clinical inte...
The analysis of rare chromosomal transloca-tions in myeloproliferative disorders has highlighted the...
JAK2 is a tyrosine kinase that plays an important role in the signaling pathways of many hematopoiet...
The analysis of rare chromosomal translocations in myeloproliferative disorders has highlighted the ...
Chronic Myeloid Leukaemia (CML) is characterized by BCR-ABL1 mutation. A number of research studies ...
Introduction: The myeloproliferative neoplasms (MPNs) are a heterogeneous group of diseases characte...
We studied the relationship between JAK2 (V617F) mutant allele burden and clinical phenotype, diseas...
In July, 2000, a 50-year-old man presented with leukocytosis and splenomegaly (21 cm). Leucocyte con...
Different methods using peripheral blood RNA (Vannucchi AM, et al. Leukemia. 2007,1–8), or archival ...
The JAK2V617F mutation is an essential oncogenic event in Philadelphia negative chronic myeloprolife...
TO THE EDITOR Several groups have recently reported the presence of a unique gain-of-function JAK2 p...
The aim of this study was to investigate the presence of Janus kinase 2 (JAK2) V617F mutation in pat...
Objective: The JAK2V617F mutation is present in the majority of patients with essential thrombocyth...
<p>ALL: acute lymphatic leukemia; AML: acute myeloid leukemia; sAML: secondary AML; CLL; chronic lym...
Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy characterized by myelopr...
Since low JAK2V617F allele burden (AB) has been detected also in healthy subjects, its clinical inte...
The analysis of rare chromosomal transloca-tions in myeloproliferative disorders has highlighted the...
JAK2 is a tyrosine kinase that plays an important role in the signaling pathways of many hematopoiet...
The analysis of rare chromosomal translocations in myeloproliferative disorders has highlighted the ...
Chronic Myeloid Leukaemia (CML) is characterized by BCR-ABL1 mutation. A number of research studies ...
Introduction: The myeloproliferative neoplasms (MPNs) are a heterogeneous group of diseases characte...
We studied the relationship between JAK2 (V617F) mutant allele burden and clinical phenotype, diseas...
In July, 2000, a 50-year-old man presented with leukocytosis and splenomegaly (21 cm). Leucocyte con...
Different methods using peripheral blood RNA (Vannucchi AM, et al. Leukemia. 2007,1–8), or archival ...
The JAK2V617F mutation is an essential oncogenic event in Philadelphia negative chronic myeloprolife...
TO THE EDITOR Several groups have recently reported the presence of a unique gain-of-function JAK2 p...
The aim of this study was to investigate the presence of Janus kinase 2 (JAK2) V617F mutation in pat...
Objective: The JAK2V617F mutation is present in the majority of patients with essential thrombocyth...