RP-220 alters the pattern of MAPK activation in cisplatin treated cells.

<p>A, MAPK phosphorylation with cisplatin alone (CP) and with CP and RP-220, representative study, p-p38: phosphorylated p38 MAPK; p-ERK: phosphorylated ERK. B, Quantification of ERK activation, signals normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) loading control; n = 3, * = P<0.05. C, Quantification of p38 activation, signals normalized to GAPDH loading control; n = 3, * = P<0.05.