<p>Expressions of different genes were detected by the Human Prime View Array technology in MIA PaCa-2 cells after 24 hours PA treatment with PA (0 and 30 μM) in quadruplicates. Gene expression levels were normalized and analyzed using Microarray Data Portal (MDP) by 2-way ANOVA using cell line and treatment as factors plus the interaction of cell line and treatment. A q-value program from Storey and Tibshirani was used to calculate false discovery rates. Fold change P < 1E-05.</p><p>PA upregulates expression of ER stress related genes.</p
<p>(A) PANC-1 and (B) MIA PaCa-2 cells were treated with or without PA (30 μM) in presence of TUDCA ...
Genes of interest are shown that are known to be directly involved in (A) oxidative stress response;...
<p>(A) The top three genes with the strongest strain effect. Horizontal line represents 1.5 fold. Fo...
<p>Quantitative real time PCR (Q-PCR) measurement of mRNA level expression of five stress-response r...
<p>(A) RT-PCR analysis of VEGFA and β-actin in ARPE-19 cells treated with ER stressors (1 µM thapsig...
<p>Representative of ER stress genes deregulated in both the microarray from Siah1a/2 KO MEF cells a...
<p>Animal experiments were performed as described in <a href="http://www.plosone.org/article/info:do...
<p>A2780 cells were treated with 7 μM t10,c12 CLA for 72 h. Control cells were treated with vehicle ...
<p><b>A</b>. Principal component analysis of microarray data obtained by hybridization of mRNA extra...
Background: The unfolded protein response (UPR) refers to intracellular stress signaling pathways th...
The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) results in the ...
<p>(A) Conditioned media from HepG2.2.15 (2.2.15-CM) and conditioned media from HepG2 (HepG2-CM) wer...
The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) results in the ...
<p>(A) Representative photographs of the nuclei of podocytes treated with vehicle, 100, 500 or 750 μ...
<p>HUVECs (from four individuals) were stimulated with 4 mM VPA for 24 h and mRNA from treated and u...
<p>(A) PANC-1 and (B) MIA PaCa-2 cells were treated with or without PA (30 μM) in presence of TUDCA ...
Genes of interest are shown that are known to be directly involved in (A) oxidative stress response;...
<p>(A) The top three genes with the strongest strain effect. Horizontal line represents 1.5 fold. Fo...
<p>Quantitative real time PCR (Q-PCR) measurement of mRNA level expression of five stress-response r...
<p>(A) RT-PCR analysis of VEGFA and β-actin in ARPE-19 cells treated with ER stressors (1 µM thapsig...
<p>Representative of ER stress genes deregulated in both the microarray from Siah1a/2 KO MEF cells a...
<p>Animal experiments were performed as described in <a href="http://www.plosone.org/article/info:do...
<p>A2780 cells were treated with 7 μM t10,c12 CLA for 72 h. Control cells were treated with vehicle ...
<p><b>A</b>. Principal component analysis of microarray data obtained by hybridization of mRNA extra...
Background: The unfolded protein response (UPR) refers to intracellular stress signaling pathways th...
The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) results in the ...
<p>(A) Conditioned media from HepG2.2.15 (2.2.15-CM) and conditioned media from HepG2 (HepG2-CM) wer...
The accumulation of unfolded or misfolded proteins in the endoplasmic reticulum (ER) results in the ...
<p>(A) Representative photographs of the nuclei of podocytes treated with vehicle, 100, 500 or 750 μ...
<p>HUVECs (from four individuals) were stimulated with 4 mM VPA for 24 h and mRNA from treated and u...
<p>(A) PANC-1 and (B) MIA PaCa-2 cells were treated with or without PA (30 μM) in presence of TUDCA ...
Genes of interest are shown that are known to be directly involved in (A) oxidative stress response;...
<p>(A) The top three genes with the strongest strain effect. Horizontal line represents 1.5 fold. Fo...