Resveratrol induces premature senescence in BJ fibroblasts.

<p>Cells were either left untreated, <b>C</b> (control), or treated with <b>D,</b> (DMSO) or 10, 25, 50 and 100 μM of Resveratrol for 72 h (A) used for assessment of SA-β-gal activity. SA-b-gal staining increased with RV doses in BJ cells (B) The percentage of SA-β-gal positive senescent cells in RV-treated and control or DMSO treated cells is presented as mean ± s.d of three independent experiments. The data represent the average and standard deviation of three independent counts of 100 cells each. Mean ± s.d. of three independent experiment of is shown, ** represents p<0,01 using the Student’s <i>t</i>-test.