<p>Microglia was stimulated either with anti-CLM-1 Ab or an isotypic control together with LPS (100 ng/mL). Supernatants were recovered 24 hours later and protein levels were measured by ELISA. Data are presented as mean ± SEM of 4 independent experiments. Statistically significant differences between treatments were determined by one-way ANOVA followed by Newman Keuls post-test. *P < 0.05 compared to IgG.</p
<p>Saline (20 µl/paw) or LPS (100 ng/paw) was injected into the TNFR1<sup>+/+</sup> (C57BL/6 backgro...
<p>LPS primed microglia were stimulated with ATP (1 mM, 30 min), Nigericin (Nig, 1.34 μM, 2 h), Mono...
<p>Cells were pre-treated with 10 mM GSH-C4 or NAC for 2 h, washed and then LPS was added for 24 h. ...
<p>Microglia was stimulated either with anti-CLM-1 Ab or an isotypic control in combination with LPS...
<p>BM and SCM were activated with LPS to measure the difference in their pro-inflammatory molecules ...
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that i...
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that i...
<p><b>A)</b> Genomic organization and splicing pattern of CLM-1. A diagram representing CLM-1 splice...
<p><b>A)</b> QT-PCR analysis of CLM-1 transcript was performed on primary microglia total RNA. RAW26...
<p><b>A</b>. IL-6 release was determined by ELISA in culture supernatants harvested 3 h, 6 h and 24 ...
<p>IL-1β (a), TNF-α (b), IL-6 (c), IL-1ra (d), corticosterone (e) and PGEM (f) as measured by ELISA ...
<p>Data are shown as mean ± SEM for 6 mice per treatment group. Clear bars represent PBS-treated mic...
Microglia respond to CNS injuries and diseases with complex reactions, often called “activation.” A ...
<p>Mice were pre-treated with individual or combined anti-TLR2 or anti-TLR4 antibodies (45 minutes b...
<p>(A) Representative images of microglia following 10 μM cordycepin treatment for 1 day with or wit...
<p>Saline (20 µl/paw) or LPS (100 ng/paw) was injected into the TNFR1<sup>+/+</sup> (C57BL/6 backgro...
<p>LPS primed microglia were stimulated with ATP (1 mM, 30 min), Nigericin (Nig, 1.34 μM, 2 h), Mono...
<p>Cells were pre-treated with 10 mM GSH-C4 or NAC for 2 h, washed and then LPS was added for 24 h. ...
<p>Microglia was stimulated either with anti-CLM-1 Ab or an isotypic control in combination with LPS...
<p>BM and SCM were activated with LPS to measure the difference in their pro-inflammatory molecules ...
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that i...
CMRF35-like molecule-1 (CLM-1) belongs to a receptor family mainly expressed in myeloid cells that i...
<p><b>A)</b> Genomic organization and splicing pattern of CLM-1. A diagram representing CLM-1 splice...
<p><b>A)</b> QT-PCR analysis of CLM-1 transcript was performed on primary microglia total RNA. RAW26...
<p><b>A</b>. IL-6 release was determined by ELISA in culture supernatants harvested 3 h, 6 h and 24 ...
<p>IL-1β (a), TNF-α (b), IL-6 (c), IL-1ra (d), corticosterone (e) and PGEM (f) as measured by ELISA ...
<p>Data are shown as mean ± SEM for 6 mice per treatment group. Clear bars represent PBS-treated mic...
Microglia respond to CNS injuries and diseases with complex reactions, often called “activation.” A ...
<p>Mice were pre-treated with individual or combined anti-TLR2 or anti-TLR4 antibodies (45 minutes b...
<p>(A) Representative images of microglia following 10 μM cordycepin treatment for 1 day with or wit...
<p>Saline (20 µl/paw) or LPS (100 ng/paw) was injected into the TNFR1<sup>+/+</sup> (C57BL/6 backgro...
<p>LPS primed microglia were stimulated with ATP (1 mM, 30 min), Nigericin (Nig, 1.34 μM, 2 h), Mono...
<p>Cells were pre-treated with 10 mM GSH-C4 or NAC for 2 h, washed and then LPS was added for 24 h. ...