Biofilm formation.

<p>Growth and biofilm formation by <i>S</i>. <i>pneumoniae</i> clinical isolates of the indicated serotypes, and their encapsulated M11 transformants. In all cases, open bars indicate bacterial growth. Hatched and blackened bars indicate, respectively, biofilm formation by either clinical isolates or their encapsulated M11 transformants. Grey bars correspond to biofilm formation by the M11 strain. Biofilm formation by the M11 strain was determined in all experiments with mean values between serotypes that were not significantly different (<i>P</i> >0.05 using one-way ANOVA).