<p>Morphometric analysis using Ki67, a proliferation marker in kidney medulla of vehicle (CON)- and DAPA-treated PCK rats. Data are expressed as means ± SE.</p><p>Effect of DAPA on cell proliferation in PCK rat kidneys.</p
Some nongenotoxic chemicals which cause kidney tumors have been shown to stimulate tubular cell prol...
The sodium-glucose-cotransporter-2 (SGLT2) inhibitor dapagliflozin (DAPA) induces glucosuria and osm...
<p>Mesangial cells were cultured and treated with vehicle or S1P together with sera from control rat...
<p>Representative areas of Ki67 immunohistochemical staining in PCK rat kidneys are shown. Nuclei of...
<p>Representative renal histology by periodic acid-Schiff (PAS) staining of kidneys in vehicle- trea...
<p>Data are expressed as means ± SE. CON, vehicle control; DAPA, dapagliflozin.</p><p>*<i>P</i><0.05...
<p>Ratio of two kidney weights to total body weight (2KW/TBW) (A), cyst index (B) and number of cyst...
<p>Typical 2D transverse power Doppler ultrasound images of a kidney in CON- and DAPA-treated PCK ra...
<p>Analysis of cAMP concentration per mg protein in PCK rat kidneys treated with vehicle (CON) or da...
<p>Data are expressed as means ± SE. CON, vehicle control; DAPA, dapagliflozin.</p><p>*<i>P</i><0.05...
<p>Data are expressed as means ± SE. CON, vehicle control; DAPA, dapagliflozin.</p><p>*<i>P</i><0.05...
<p>Urine protein analysis by SDS-PAGE from urine samples of PCK rats after 6 weeks of treatment with...
<p><b>A.</b> Immunohistochemical and immunofluorescence staining were used to determine the expressi...
<p>Kidney sections of <b>PDC-treated group (a, b, c)</b> showing significant increase of PCNA-positi...
<p>(A–D) PCNA immunohistochemistry staining in pulmonary artery strips (×400, nuclear staining): (A)...
Some nongenotoxic chemicals which cause kidney tumors have been shown to stimulate tubular cell prol...
The sodium-glucose-cotransporter-2 (SGLT2) inhibitor dapagliflozin (DAPA) induces glucosuria and osm...
<p>Mesangial cells were cultured and treated with vehicle or S1P together with sera from control rat...
<p>Representative areas of Ki67 immunohistochemical staining in PCK rat kidneys are shown. Nuclei of...
<p>Representative renal histology by periodic acid-Schiff (PAS) staining of kidneys in vehicle- trea...
<p>Data are expressed as means ± SE. CON, vehicle control; DAPA, dapagliflozin.</p><p>*<i>P</i><0.05...
<p>Ratio of two kidney weights to total body weight (2KW/TBW) (A), cyst index (B) and number of cyst...
<p>Typical 2D transverse power Doppler ultrasound images of a kidney in CON- and DAPA-treated PCK ra...
<p>Analysis of cAMP concentration per mg protein in PCK rat kidneys treated with vehicle (CON) or da...
<p>Data are expressed as means ± SE. CON, vehicle control; DAPA, dapagliflozin.</p><p>*<i>P</i><0.05...
<p>Data are expressed as means ± SE. CON, vehicle control; DAPA, dapagliflozin.</p><p>*<i>P</i><0.05...
<p>Urine protein analysis by SDS-PAGE from urine samples of PCK rats after 6 weeks of treatment with...
<p><b>A.</b> Immunohistochemical and immunofluorescence staining were used to determine the expressi...
<p>Kidney sections of <b>PDC-treated group (a, b, c)</b> showing significant increase of PCNA-positi...
<p>(A–D) PCNA immunohistochemistry staining in pulmonary artery strips (×400, nuclear staining): (A)...
Some nongenotoxic chemicals which cause kidney tumors have been shown to stimulate tubular cell prol...
The sodium-glucose-cotransporter-2 (SGLT2) inhibitor dapagliflozin (DAPA) induces glucosuria and osm...
<p>Mesangial cells were cultured and treated with vehicle or S1P together with sera from control rat...