<p>Clot retraction of washed platelets was intiated by adding thrombin (0.1 U/ml) in the presence or absence of TRPC6 inhibitor (10 μM) and photographed for every 10 minutes up to one hour (n = 4).</p
<p>(A) Platelet adhesion and spreading on collagen were carried out as described under Materials and...
<p>(A) Exposure of PS by R-6G labeled platelets (red) in the presence of either (i) FK633 (30 µM), (...
AbstractThe integrin αIIbβ3 plays a critical role in mediating clot retraction by platelets which is...
<p>PRP was incubated without or with the TRPC6 inhibitor (5 μM and/or 10 μM) for 5 min followed by s...
<p>Washed platelets were incubated in the presence or absence of TRPC6 inhibitor (10 μM) for 5 minut...
Platelets have important functions in hemostasis. Best investigated is the aggregation of platelets ...
The effects of inhibitors of mitosis, energy metabolism and protein synthesis on clot retrac-tion we...
Rate and extent of clot retraction are determining factors in either causing or preventing damage in...
<p>PRP was incubated without or with TRPC6 inhibitor (10 μM) for 5 min followed by stimulation of PR...
<p>(A) Human platelets were loaded with Fura-2/AM to measure intracellular [Ca<sup>2+</sup>]<sub>i</...
The study of clot retraction in vitro has been adopted as a simple and reproducible approach to asse...
<p>Binding displacement of 1 nM [<sup>3</sup>H]SQ29,548 with increasing concentrations of the TRPC6 ...
<p>(A) Platelets were washed and resuspended at 1 × 10<sup>8</sup>/mL in buffer (see “Experimental P...
<p>(A) CLSM images obtained at the level of 3 µm from the bottom of the dish 60 minutes after supple...
<p>Mice were injected with TRPC6 inhibitor (10 μM) or vehicle 1 hour before their tail bleeding time...
<p>(A) Platelet adhesion and spreading on collagen were carried out as described under Materials and...
<p>(A) Exposure of PS by R-6G labeled platelets (red) in the presence of either (i) FK633 (30 µM), (...
AbstractThe integrin αIIbβ3 plays a critical role in mediating clot retraction by platelets which is...
<p>PRP was incubated without or with the TRPC6 inhibitor (5 μM and/or 10 μM) for 5 min followed by s...
<p>Washed platelets were incubated in the presence or absence of TRPC6 inhibitor (10 μM) for 5 minut...
Platelets have important functions in hemostasis. Best investigated is the aggregation of platelets ...
The effects of inhibitors of mitosis, energy metabolism and protein synthesis on clot retrac-tion we...
Rate and extent of clot retraction are determining factors in either causing or preventing damage in...
<p>PRP was incubated without or with TRPC6 inhibitor (10 μM) for 5 min followed by stimulation of PR...
<p>(A) Human platelets were loaded with Fura-2/AM to measure intracellular [Ca<sup>2+</sup>]<sub>i</...
The study of clot retraction in vitro has been adopted as a simple and reproducible approach to asse...
<p>Binding displacement of 1 nM [<sup>3</sup>H]SQ29,548 with increasing concentrations of the TRPC6 ...
<p>(A) Platelets were washed and resuspended at 1 × 10<sup>8</sup>/mL in buffer (see “Experimental P...
<p>(A) CLSM images obtained at the level of 3 µm from the bottom of the dish 60 minutes after supple...
<p>Mice were injected with TRPC6 inhibitor (10 μM) or vehicle 1 hour before their tail bleeding time...
<p>(A) Platelet adhesion and spreading on collagen were carried out as described under Materials and...
<p>(A) Exposure of PS by R-6G labeled platelets (red) in the presence of either (i) FK633 (30 µM), (...
AbstractThe integrin αIIbβ3 plays a critical role in mediating clot retraction by platelets which is...