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Comparison of gene expression differences between samples from patients with OA, RA and SA, using high-density arrays versus qPCR.

  • Bernard R. Lauwerys (134715)
  • Daniel Hernández-Lobato (732978)
  • Pierre Gramme (732979)
  • Julie Ducreux (732980)
  • Adrien Dessy (732981)
  • Isabelle Focant (732982)
  • Jérôme Ambroise (3498626)
  • Bertrand Bearzatto (732983)
  • Adrien Nzeusseu Toukap (732984)
  • Benoît J. Van den Eynde (5663422)
  • Dirk Elewaut (68008)
  • Jean-Luc Gala (396991)
  • Patrick Durez (11540)
  • Frédéric A. Houssiau (732985)
  • Thibault Helleputte (732986)
  • Pierre Dupont (469489)
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Publication date
April 2015
Icon DOI
10.1371/journal.pone.0122104.g006

Abstract

<p>Independent sets of samples were hybridized on high-density (HGU133 Plus 2.0 GeneChip) and analyzed by qPCR (Taqman low density array). (A) Differences in mean (log2-transformed) gene expression values between OA and (RA+SA) samples are displayed for the samples analyzed using high-density arrays (x axis) versus qPCR (y axis). (B) The same data from OA and (RA+SA) samples are displayed after normalization of each mean (log2-transformed) gene expression value by its standard deviation.</p

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