<p><i>RANKL</i> (A), <i>OPG</i> (B), <i>OC</i> (C), <i>COL1A</i> (D), <i>MMP-2</i> (E), and <i>MMP-9</i> (F) mRNA expression in bone tissue of control, type 1 diabetes mellitus (T1DM), and T1DM plus zinc supplementation (T1DMS) rats. All data are expressed as fold-change vs. control group values, normalized to <i>GAPDH</i>. Comparisons between groups were analyzed with Kruskal-Wallis ANOVA on Ranks and Dunn’s post-hoc. <i>p</i> < 0.05*<sup>/#</sup> vs. control group; <i>p</i> < 0.01*<sup>/##</sup> vs. control group.</p
Several studies have established an association between diabetes and alterations in bone metabolism;...
Background: Diabetes is a serious and important public health problem, especially in relation to den...
Background and purposeDiabetes mellitus (DM) is the most common metabolic disorder that is character...
<p>Trabecular separation (TbSP, μm) (A), trabecular width (TbWi, μm) (B), and trabecular bone area (...
<p>As in Fig. 1, representative agarose gel analyses of RT-PCR for expression of genes as indicated ...
<p>mRNA quantifications were performed by qRT-PCR; fold changes mRNA of treated versus control rat t...
<p>T1DM, type 1 diabetes mellitus; T1DMS, T1DM plus zinc supplementation. All data are shown as mean...
<p>(A) Real-time PCR shows relative RANKL gene expression in bone from four different diet rat group...
Relative mRNA levels normalized to Gapdh mRNA in hyperuricemic rats (closed columns) are shown as th...
<p>Expression levels of col 1α1, col 1α2, desmin, E-cadherin, fibronectin, TGF-β1, ZEB1, ZEB2 and ZO...
<p>(A) Measurement of Cu/Zn-superoxide dismutase (SOD1) and (B) gluthathione peroxidase (Gpx1) mRNA ...
<p><b>Panels A and B:</b> Representative immunoblotting (upper panels) and densitometric quantificat...
<p><sup>*)</sup>DM/TENS group and DM group P<0.01.</p><p><sup>**)</sup>DM/TENS group and Control gro...
<p>Data are representative of three independent experiments. Statistical significance between male a...
autoimmune process in bone? Gene expression studies in diabetic and nondiabetic BB rats as well as B...
Several studies have established an association between diabetes and alterations in bone metabolism;...
Background: Diabetes is a serious and important public health problem, especially in relation to den...
Background and purposeDiabetes mellitus (DM) is the most common metabolic disorder that is character...
<p>Trabecular separation (TbSP, μm) (A), trabecular width (TbWi, μm) (B), and trabecular bone area (...
<p>As in Fig. 1, representative agarose gel analyses of RT-PCR for expression of genes as indicated ...
<p>mRNA quantifications were performed by qRT-PCR; fold changes mRNA of treated versus control rat t...
<p>T1DM, type 1 diabetes mellitus; T1DMS, T1DM plus zinc supplementation. All data are shown as mean...
<p>(A) Real-time PCR shows relative RANKL gene expression in bone from four different diet rat group...
Relative mRNA levels normalized to Gapdh mRNA in hyperuricemic rats (closed columns) are shown as th...
<p>Expression levels of col 1α1, col 1α2, desmin, E-cadherin, fibronectin, TGF-β1, ZEB1, ZEB2 and ZO...
<p>(A) Measurement of Cu/Zn-superoxide dismutase (SOD1) and (B) gluthathione peroxidase (Gpx1) mRNA ...
<p><b>Panels A and B:</b> Representative immunoblotting (upper panels) and densitometric quantificat...
<p><sup>*)</sup>DM/TENS group and DM group P<0.01.</p><p><sup>**)</sup>DM/TENS group and Control gro...
<p>Data are representative of three independent experiments. Statistical significance between male a...
autoimmune process in bone? Gene expression studies in diabetic and nondiabetic BB rats as well as B...
Several studies have established an association between diabetes and alterations in bone metabolism;...
Background: Diabetes is a serious and important public health problem, especially in relation to den...
Background and purposeDiabetes mellitus (DM) is the most common metabolic disorder that is character...