<p>A red peak reaching a 1.0 max score of statistical significance depicts a homozygous region on chromosome 19. The region coincides with the 0.49 Mbp locus identified using two-point linkage analysis and is bracketed by recombination spots (indicated in red). The identified haploblock fulfills the zygosity criterion by displaying homozygosity in affected animals (indicated in red) and heterozygosity in unaffected carriers (indicated in green).</p
ABSTRACT: Homozygosity mapping has played an impor-tant role in detecting recessive mutations using ...
Recent studies of human populations suggest that the genome consists of chromosome segments that are...
The number of SNPs per 5kb window are depicted in red if the percentage of heterozygous SNPs was gre...
<p>Mean homozygosity of SNPs in a sliding window (200-kb window at 100-kb steps) was plotted versus ...
The identification of recessive disease-causing genes by homozygosity mapping is often restricted by...
Objective: Analyze the information contained in homozygous haplotypes detected with high density gen...
<p>The values of −log<sub>10</sub>(p) at the anchor SNPs for the three genome-wide homozygosity asso...
<p>Using two-point linkage analysis, a maximum LOD<sub>two-point</sub> score of 3.07 was achieved fo...
<p>(A) Manhattan plot for the haplotype-based genome-wide association study for stunted growth using...
<p>The regions of extended homozygosity on Chromosomes 3 (upper panel) and 18 (lower panel) are outl...
Previous investigations have reported linkage disequilibrium occurring between nearby polymorphisms,...
<p>(<b>A</b>) The cytogenetic location, genomic coordinates (hg19) and sizes of each ROH. (<b>B</b>)...
a<p>: Core haplotypes involved in each core region determined by Sweep across genome.</p
We used LDMAP (Maniatis et al. 2002) to analyse SNP data spanning chromosome 22 (Dawson et al. 2002)...
Recent studies of human populations suggest that the genome consists of chromosome segments that are...
ABSTRACT: Homozygosity mapping has played an impor-tant role in detecting recessive mutations using ...
Recent studies of human populations suggest that the genome consists of chromosome segments that are...
The number of SNPs per 5kb window are depicted in red if the percentage of heterozygous SNPs was gre...
<p>Mean homozygosity of SNPs in a sliding window (200-kb window at 100-kb steps) was plotted versus ...
The identification of recessive disease-causing genes by homozygosity mapping is often restricted by...
Objective: Analyze the information contained in homozygous haplotypes detected with high density gen...
<p>The values of −log<sub>10</sub>(p) at the anchor SNPs for the three genome-wide homozygosity asso...
<p>Using two-point linkage analysis, a maximum LOD<sub>two-point</sub> score of 3.07 was achieved fo...
<p>(A) Manhattan plot for the haplotype-based genome-wide association study for stunted growth using...
<p>The regions of extended homozygosity on Chromosomes 3 (upper panel) and 18 (lower panel) are outl...
Previous investigations have reported linkage disequilibrium occurring between nearby polymorphisms,...
<p>(<b>A</b>) The cytogenetic location, genomic coordinates (hg19) and sizes of each ROH. (<b>B</b>)...
a<p>: Core haplotypes involved in each core region determined by Sweep across genome.</p
We used LDMAP (Maniatis et al. 2002) to analyse SNP data spanning chromosome 22 (Dawson et al. 2002)...
Recent studies of human populations suggest that the genome consists of chromosome segments that are...
ABSTRACT: Homozygosity mapping has played an impor-tant role in detecting recessive mutations using ...
Recent studies of human populations suggest that the genome consists of chromosome segments that are...
The number of SNPs per 5kb window are depicted in red if the percentage of heterozygous SNPs was gre...