<p>We checked the distribution of HBV genotype C HCC risk mutations among sequences from different disease phases (ASC, 18; CHB, 38; LC, 27; HCC, 144). Those mutations showed characteristics among different phases: 1) except three mutations (1479T, 1631T, and 1800C) all the other mutations pre-existed in ASC, among which 1383C and 1719T were most pronounced. More than 50% ASC possessed either one of these two mutations and 42% ASC possessed both; 2) the frequency of four mutations (1485T, 1631T, 1762T, and 1764A) showed an increasing trend accompanied with the disease progression though the changes among groups were not significant (Jonckheere-Terpstra trend test, <i>P</i> > 0.05); and 3) ratios of 4 mutations (1383C, 1479C, 1479T, and 1719...
none8noWe investigated the replicative profile of hepatitis B (HBV) and hepatitis C (HCV) viruses an...
HBV is characterized by a high genetic variability, which is the basis of its classification into ei...
Understanding within-host evolution is critical for predicting viral evolutionary outcomes, yet such...
<p>*Other mutations in the preCore region that abolish HBeAg expression. No significant difference w...
<p><sup>a</sup>Mutated nucleotides are shown in bold.</p><p>B cell epitope: region (aa positions 29–...
Mutations in hepatitis B virus (HBV) X region (HBx) play important roles in hepatocarcinogenesis whi...
<p>NB: A- CHB Vs Others , B- LC Vs Others, C- HCC Vs Others, D- AC Vs Others.</p
To analyze the association between mutation(s) in preS region of HBV and hepatitis B disease progres...
To evaluate how hepatitis B virus (HBV) genetic variation affected progression from chronic carrier ...
<p><b>(a).</b> the comparison of chromosomal aberration profiles between HBV-related HCCs and HCV-re...
a<p>A mutation was defined through comparisons with the consensus sequence of HBV strains in our coh...
Most cases of hepatocellular carcinoma (HCC) are due to chronic hepatitis B virus (HBV) or hepatitis...
A two stage study was conducted to explore new potential mutations in the full genome of hepatitis B...
We performed genetic and phenic analyses to evaluate nucleotide and amino-acid sequences of the amin...
<p>The mutation distribution in 13 of the 18 HCM causative genes based on mutation class, including ...
none8noWe investigated the replicative profile of hepatitis B (HBV) and hepatitis C (HCV) viruses an...
HBV is characterized by a high genetic variability, which is the basis of its classification into ei...
Understanding within-host evolution is critical for predicting viral evolutionary outcomes, yet such...
<p>*Other mutations in the preCore region that abolish HBeAg expression. No significant difference w...
<p><sup>a</sup>Mutated nucleotides are shown in bold.</p><p>B cell epitope: region (aa positions 29–...
Mutations in hepatitis B virus (HBV) X region (HBx) play important roles in hepatocarcinogenesis whi...
<p>NB: A- CHB Vs Others , B- LC Vs Others, C- HCC Vs Others, D- AC Vs Others.</p
To analyze the association between mutation(s) in preS region of HBV and hepatitis B disease progres...
To evaluate how hepatitis B virus (HBV) genetic variation affected progression from chronic carrier ...
<p><b>(a).</b> the comparison of chromosomal aberration profiles between HBV-related HCCs and HCV-re...
a<p>A mutation was defined through comparisons with the consensus sequence of HBV strains in our coh...
Most cases of hepatocellular carcinoma (HCC) are due to chronic hepatitis B virus (HBV) or hepatitis...
A two stage study was conducted to explore new potential mutations in the full genome of hepatitis B...
We performed genetic and phenic analyses to evaluate nucleotide and amino-acid sequences of the amin...
<p>The mutation distribution in 13 of the 18 HCM causative genes based on mutation class, including ...
none8noWe investigated the replicative profile of hepatitis B (HBV) and hepatitis C (HCV) viruses an...
HBV is characterized by a high genetic variability, which is the basis of its classification into ei...
Understanding within-host evolution is critical for predicting viral evolutionary outcomes, yet such...