<p>(B) 4–5 months old male GTT and AUC (inset) in control (n = 10) and IR/LepR<sup>Kiss</sup> (n = 8) mice. (C) 5–6 months old female ITT and AUC (inset) in control and IR/LepR<sup>Kiss</sup> mice (n = 7). (D) 5–6 months old male ITT and AUC (inset) in control (n = 11) and IR/LepR<sup>Kiss</sup> (n = 7) mice.</p
<p>Serum glucose concentrations (mmol/L) following administration of glucose load (2 g/kg body weigh...
<p>(A) Female body weight growth curve after HFD (n = 8, 8). Body weights of a low-fat diet cohort i...
<p>Results for floxed control (FC) mice are shown in black and LARNT mice in white (bars or circles)...
<p>(A) Weekly body weight of female mice (Control n = 15 and IR/LepR<sup>Kiss</sup> n = 8) mice (B) ...
<p>A-F. Fluorescence photomicrographs showing the distribution of Kiss1 (hrGFP) and LepR (tdTomato) ...
<p>(A) Female representative <i>Kiss1</i> immunostaining: Upper left square = AVPV/PeN of control mo...
<p>A. Agarose gel showing Cre-induced DNA recombination (higher band) of LepR<i><sup>Lox</sup></i><s...
<p>Controls, white bars or open circles; TgCEL mice, black bars or filled circles. Results are given...
<p>(A,B) Fasting blood glucose (A) and insulin levels (B) in male non-progressing mice 30 weeks of a...
<p>A-C. Brightfield photomicrographs showing the distribution of leptin-induced phosphorylation of S...
<p>(<b>A</b>) Blood glucose levels in WT, <i>Mbd5<sup>+/−</sup></i> and <i>Mbd5<sup>−/−</sup></i> mi...
<p>A-F. Fluorescence photomicrographs showing the distribution of Cre activity (Kiss1 reporter gene)...
<p>A) <i>L-PGDS</i> mRNA levels in the major metabolic tissues of <i>PPARγ2</i> KO mice. B) Body wei...
<p>Body weight of 6 month old male and female LERKO mice was comparable to respective CT mice (A). L...
(A) Blood glucose quantification in 2 and 6 months old mice measured in overnight fasted and fed sta...
<p>Serum glucose concentrations (mmol/L) following administration of glucose load (2 g/kg body weigh...
<p>(A) Female body weight growth curve after HFD (n = 8, 8). Body weights of a low-fat diet cohort i...
<p>Results for floxed control (FC) mice are shown in black and LARNT mice in white (bars or circles)...
<p>(A) Weekly body weight of female mice (Control n = 15 and IR/LepR<sup>Kiss</sup> n = 8) mice (B) ...
<p>A-F. Fluorescence photomicrographs showing the distribution of Kiss1 (hrGFP) and LepR (tdTomato) ...
<p>(A) Female representative <i>Kiss1</i> immunostaining: Upper left square = AVPV/PeN of control mo...
<p>A. Agarose gel showing Cre-induced DNA recombination (higher band) of LepR<i><sup>Lox</sup></i><s...
<p>Controls, white bars or open circles; TgCEL mice, black bars or filled circles. Results are given...
<p>(A,B) Fasting blood glucose (A) and insulin levels (B) in male non-progressing mice 30 weeks of a...
<p>A-C. Brightfield photomicrographs showing the distribution of leptin-induced phosphorylation of S...
<p>(<b>A</b>) Blood glucose levels in WT, <i>Mbd5<sup>+/−</sup></i> and <i>Mbd5<sup>−/−</sup></i> mi...
<p>A-F. Fluorescence photomicrographs showing the distribution of Cre activity (Kiss1 reporter gene)...
<p>A) <i>L-PGDS</i> mRNA levels in the major metabolic tissues of <i>PPARγ2</i> KO mice. B) Body wei...
<p>Body weight of 6 month old male and female LERKO mice was comparable to respective CT mice (A). L...
(A) Blood glucose quantification in 2 and 6 months old mice measured in overnight fasted and fed sta...
<p>Serum glucose concentrations (mmol/L) following administration of glucose load (2 g/kg body weigh...
<p>(A) Female body weight growth curve after HFD (n = 8, 8). Body weights of a low-fat diet cohort i...
<p>Results for floxed control (FC) mice are shown in black and LARNT mice in white (bars or circles)...