<p>Mice were subjected to 90min of partial liver ischemia, followed by 0h, 1h, 3h and 6h reperfusion. Kinetics of IL-11 gene expression was analyzed in ischemic liver by RT-PCR. Expression of IL-11 was normalized with that of HPRT. Data are expressed as mean±SD (n = 6/group). *P<0.05, **P<0.001 vs sham group.</p
<p>The effect of H11 on the numbers of spleen BFU-E, CFU-GM, CFU-GEMM and CFU-Mk compared with the a...
<p>BALB/c mice were treated with 1 µg/mouse IL-12 (solid square) or vehicle control (VC; open triang...
<p>(A) There was a significantly higher level of IL1β in GFPWT:WT mice treated with LPS compared to ...
<p>Mice were administered with recombinant human IL-IL-11 (500μg/kg, ip) or medium (PBS) 1 hour prio...
The protective role of IL-11, an IL-6 family cytokine, has been implicated in ischemia/reperfusion i...
<p>Mice were injected with STAT3 siRNA or NS siRNA 4h prior to ischemia, and administered with IL-11...
(A) Hepatocytes were stimulated by IL-11. RNA samples collected 16 hr after stimulation were subject...
<p><b><i>A, B,</i></b> Individual C57BL6/J mice were administered IVIg (2.0 g/kg) or PBS. <b><i>A</i...
<p>(A) IL-11 was administered in mice for the indicated time. The lysates from liver were immunoblot...
<p>(A)Liver apoptosis was examined by TUNEL staining: Sham group, IR group and IL-11+IR group. (B) A...
<p>(A) <i>In vivo</i> administration of anti-IL-11 antibodies leads to a selective down-regulation o...
<p>(A) STAT3 gene expression was analyzed in transfected hepatocytes by RT-PCR analysis. Expressions...
<p>Male and female C57BL/6 mice were subjected to I/R (black bars) or sham-operation (white bars) wi...
Background Interleukin (IL)-33 is a recently identified member of the IL-1 family that binds to the ...
(A) qRT-PCR was performed for hepatocyte RNA samples collected at the indicated time points after IF...
<p>The effect of H11 on the numbers of spleen BFU-E, CFU-GM, CFU-GEMM and CFU-Mk compared with the a...
<p>BALB/c mice were treated with 1 µg/mouse IL-12 (solid square) or vehicle control (VC; open triang...
<p>(A) There was a significantly higher level of IL1β in GFPWT:WT mice treated with LPS compared to ...
<p>Mice were administered with recombinant human IL-IL-11 (500μg/kg, ip) or medium (PBS) 1 hour prio...
The protective role of IL-11, an IL-6 family cytokine, has been implicated in ischemia/reperfusion i...
<p>Mice were injected with STAT3 siRNA or NS siRNA 4h prior to ischemia, and administered with IL-11...
(A) Hepatocytes were stimulated by IL-11. RNA samples collected 16 hr after stimulation were subject...
<p><b><i>A, B,</i></b> Individual C57BL6/J mice were administered IVIg (2.0 g/kg) or PBS. <b><i>A</i...
<p>(A) IL-11 was administered in mice for the indicated time. The lysates from liver were immunoblot...
<p>(A)Liver apoptosis was examined by TUNEL staining: Sham group, IR group and IL-11+IR group. (B) A...
<p>(A) <i>In vivo</i> administration of anti-IL-11 antibodies leads to a selective down-regulation o...
<p>(A) STAT3 gene expression was analyzed in transfected hepatocytes by RT-PCR analysis. Expressions...
<p>Male and female C57BL/6 mice were subjected to I/R (black bars) or sham-operation (white bars) wi...
Background Interleukin (IL)-33 is a recently identified member of the IL-1 family that binds to the ...
(A) qRT-PCR was performed for hepatocyte RNA samples collected at the indicated time points after IF...
<p>The effect of H11 on the numbers of spleen BFU-E, CFU-GM, CFU-GEMM and CFU-Mk compared with the a...
<p>BALB/c mice were treated with 1 µg/mouse IL-12 (solid square) or vehicle control (VC; open triang...
<p>(A) There was a significantly higher level of IL1β in GFPWT:WT mice treated with LPS compared to ...