Summary of significant mtSNPs.

<p>Genomic position in base pairs (bp), alleles, rs_number, and point mutation are based on the NCBI dbSNP GRCh38 human genome assembly (rCRS, GeneBank ID J01415.2). Alleles are given in terms of major→minor allele. The population minor allele frequency “maf” is based on 2,704 individuals provided by mitomap (<a href="http://www.mitomap.org" target="_blank">http://www.mitomap.org</a>). Note that these allele frequency estimates do not account for the presence of heteroplasmy. An estimated effect size (β_SNP) < 0 indicates that the risk allele is the minor allele. Nominal p-values and adjusted p-values are provided. mtSNPs mt3336, mt5285 and mt14000 are also included in other chips.</p><p>Summary of significant mtSNPs.