Interactions between PARPs and PARGs.

<p>(A) PARP1 associates <i>in vivo</i> with PARP2. (B) PARG1 associates <i>in vivo</i> with PARG2. (C) PARP1 associates <i>in vivo</i> with PARG1 and PARG2. (D) PARP2 associates <i>in vivo</i> with PARG1 and PARG2. The indicated proteins were transiently expressed in <i>N</i>. <i>benthamiana</i>. Input lanes were loaded with total protein extracts, IP lanes were loaded with immunoprecipitation products. Immunoprecipitations were performed with anti-GFP antibodies and immunoblots were analyzed with anti-GFP or anti-myc antibodies, as noted. These experiments were repeated twice with similar results.