Effect of PKM2 silencing according to p53 in HT29 and HCT116 cell lines.
- Alba Ginés (2211217)
- Sara Bystrup (2211208)
- Vicenç Ruiz de Porras (2211211)
- Cristina Guardia (2211220)
- Eva Musulén (590407)
- Anna Martínez-Cardús (2211202)
- José Luis Manzano (303112)
- Laura Layos (2211223)
- Albert Abad (2211205)
- Eva Martínez-Balibrea (2211214)
Publication date
May 2015
DOIAbstract
<p>Bars represent the IC50 ± SD (average values from at least three independent experiments) for oxaliplatin for each condition. Insets show PKM2 and p53 inmunoblotting after PKM2 gene silencing. Specific IC50 values for oxaliplatin in all conditions are displayed in the table. IC50 values for Mock conditions (without transfection) were very similar to those of siNTC and are not shown. *p-values are result of comparison to the siNTC condition. * <i>P- value</i> < 0.05. ** <i>P-value <</i> 0.01; *** <i>P-value <</i> 0.001</p
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