HIF-alpha expression in involuting glands five days post weaning.

<p>Size bars: 50 μm. * marks the lymph node for orientation. 20x and 40x lenses as indicated. <b>a, A</b>. CK14 marks the basal mammary epithelial cells and stem/progenitor cells. <b>b, B</b>. CK8 positivity shows the luminal mammary epithelial cells. <b>c, C</b>. HIF-1α IHC showed weak or little positivity in mammary epithelial cells at this stage. <b>d, D</b>. HIF-2α positive cells were found in the clusters of epithelial cells. <b>e, E</b>. Macrophage (F4/80 positive) infiltration has begun by five days post weaning. F4/80 positive cells were apparently fewer than HIF-2α positive cells.