Neural response is reduced following neuropathic noise.

<p>ABR wave I peak-to-peak amplitudes (<b>a</b>) and DPOAE amplitudes (<b>b</b>) in response to 11.3 kHz tones (left column) and 32.0 kHz tones (right column) recorded from 6 hours to 16 months post exposure to noise causing PTS (100 dB SPL, purple), neuropathic noise causing TTS (97 dB SPL, blue), non-neuropathic noise causing TTS (94 dB SPL, green), and unexposed animals (red). ABR amplitudes are in response to 80 dB SPL tones (the maximum level tested) and DPOAE amplitudes are in response to 80 dB SPL tones. Noise parameters are as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0125160#pone.0125160.g001" target="_blank">Fig 1</a>. Statistical significance of the group differences is indicated by asterisks: *: <i>p < 0</i>.<i>05</i>, **: <i>p < 0</i>.<i>01</i>, ***: <i>p < 0</i>.<i>001</i>. Data are group means ± SD. N = 5–9 mice per time point for noise-exposed and control groups.