Inhibitory avoidance test analysis in sham and Nx.

<p>(A) The first exposure of animals to the inhibitory avoidance equipment and the test performed 24h after the training session. Sham and Nx groups entered the dark space in short time, showing no difference concerning the preference for this ambient but a significant difference between both groups behavior was observed in the test performed 24h after the training session. (B) All the animals were tested at 30, 60, 90 and 120 days following the 24h-test day. During the observational time, 24h-test was considered the 0 (zero) time. The latency time to cross from the light to the dark side of the chamber was measured and used as a reference to distinguish if the rats learned from a fear conditional stimulus. Animals from Sham group maintained the memory of the task and this was significantly higher than the memory of the Nx group [F_(1,129) = 5.2, P < 0.05]. Nx group showed worse performance during all observational time (B). *: P < 0.05; <i>a</i>: P < 0.001. The group was divided into Nx-M group (latencies above the median level) and Nx-Cl group (latencies under the median level) (C).