<p>Mean (standard deviation) scores on the Likert numerical pain scale over (a) 56 days and (b) 7 days (expanded time axis), and (c) mean (standard deviation) scores on the 100 mm VAS of the Short-Form McGill Pain Questionnaire over 56 days, following i.v. or s.c. administration of BG00010 or placebo. Note that Likert data were missing at day 21 for one placebo-treated subject, and both Likert and McGill data were missing at day 56 for six placebo-treated subjects and all subjects treated with BG00010 0.3, 1, 3, 10, 25 or 50 μg/kg. i.v., intravenous; s.c., subcutaneous; VAS, visual analog scale.</p
Knowledge about placebo mechanisms in patients with chronic pain is scarce. Fibromyalgia syndrome (F...
<p>The SPID was calculated as the difference between the baseline SPI-value and the SPI-value at 1 m...
Figure 1- Pain Intensity after Cutaneous Application of Menthol Analysed by Repeated Measurement Tes...
<p>Change in placebo was calculated as difference between pain scores in the placebo arm (pre-minus ...
Pearson’s correlation (r) for change in within-group pain scores over publication year at baseline: ...
<p>Pain was rated using the visual analogue scale (VAS) ranging from “no pain” (0 mm VAS) up to “wor...
<p>A (left side) show the pain scores on the CGRP days. B (Right side) show the pain scores on the p...
Participants rated their pain between 0 (no pain) and 10 (worst possible pain). The graph shows the ...
<p>Placebo treatment significantly reduced pain at 80% and 100% shock intensities. Further, the enha...
<p>All values are medians with interquartile ranges. • = Measurements after study treatment were s...
<p>All values are medians with interquartile ranges. • = Measurements after study treatment were s...
<p>All values are medians with interquartile ranges. • = Measurements after study treatment were s...
<p>Data presented as mean ± SD.</p><p>* Significant values p≤0.05.</p><p>** Significant values p≤0.0...
Bruce Parsons, Birol Emir, Andrew Clair Pfizer, New York, NY, USA Background: Pregabalin is an &alp...
Analgesic trials frequently fail to demonstrate efficacy of drugs known to be efficacious. Poor pain...
Knowledge about placebo mechanisms in patients with chronic pain is scarce. Fibromyalgia syndrome (F...
<p>The SPID was calculated as the difference between the baseline SPI-value and the SPI-value at 1 m...
Figure 1- Pain Intensity after Cutaneous Application of Menthol Analysed by Repeated Measurement Tes...
<p>Change in placebo was calculated as difference between pain scores in the placebo arm (pre-minus ...
Pearson’s correlation (r) for change in within-group pain scores over publication year at baseline: ...
<p>Pain was rated using the visual analogue scale (VAS) ranging from “no pain” (0 mm VAS) up to “wor...
<p>A (left side) show the pain scores on the CGRP days. B (Right side) show the pain scores on the p...
Participants rated their pain between 0 (no pain) and 10 (worst possible pain). The graph shows the ...
<p>Placebo treatment significantly reduced pain at 80% and 100% shock intensities. Further, the enha...
<p>All values are medians with interquartile ranges. • = Measurements after study treatment were s...
<p>All values are medians with interquartile ranges. • = Measurements after study treatment were s...
<p>All values are medians with interquartile ranges. • = Measurements after study treatment were s...
<p>Data presented as mean ± SD.</p><p>* Significant values p≤0.05.</p><p>** Significant values p≤0.0...
Bruce Parsons, Birol Emir, Andrew Clair Pfizer, New York, NY, USA Background: Pregabalin is an &alp...
Analgesic trials frequently fail to demonstrate efficacy of drugs known to be efficacious. Poor pain...
Knowledge about placebo mechanisms in patients with chronic pain is scarce. Fibromyalgia syndrome (F...
<p>The SPID was calculated as the difference between the baseline SPI-value and the SPI-value at 1 m...
Figure 1- Pain Intensity after Cutaneous Application of Menthol Analysed by Repeated Measurement Tes...