<p>(A) Representative confocal images showing JC-1 fluorescence in protoscoleces incubated under control conditions (a-d) or treated with 10 mM metformin (Met, e-h) for 48 h. tg: tegument; rc: rostellar cone; su: sucker; pb posterior bladder. Bars indicate 50 μm. (B) Boxplot graph showing the values of the red/green JC-1 fluorescence ratios measured in control (Co) and Met-treated protoscoleces by Image J Software. ***Statistically significant difference (<i>P</i> < 0.05) compared with control.</p
<p>Optical density was expressed as pTen, p53, cyclin D1, p21, Ras, Rb and E2F1 values normalized to...
Metformin is a widely prescribed drug for the treatment of type 2 diabetes. Previous studies have de...
International audienceMetformin, a drug widely used in the treatment of Type II diabetes, has recent...
<p><b>A)</b> Mouse primary hepatocytes were cultured on permanox Lab-Tek 8-well chamber slides with ...
<p><b>A)</b> Effect of metformin on cellular ATP level. Mouse primary hepatocytes were treated with ...
Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of a...
<p>Outcome data from metformin-treated groups and control groups were extracted from primary studies...
Late-phase clinical trials investigating metformin as a cancer therapy are underway. However, there ...
Late-phase clinical trials investigating metformin as a cancer therapy are underway. However, there ...
<p>(<b>A</b>) Four human GB cell lines (U87, U251, LN18 and SF767) were treated with or without metf...
<p><b>A.</b> MCF7 cells were treated with metformin (8 mM) for 15 hours in either 25 mM or 2.5 mM gl...
<p>Histochemical analysis of muscle fibers stained for NADH transferase activity. Panels A to F show...
<p>A: Representative immunoblot analysis of cyclin D1, D2 and D3 in BPH-1 cells 48 hours after treat...
<p><b>(A-B)</b> 7721 and HepG2 cells were treated with metformin for different time points up to 96 ...
International audienceMetformin is a drug from the biguanide family that is used for decades as the ...
<p>Optical density was expressed as pTen, p53, cyclin D1, p21, Ras, Rb and E2F1 values normalized to...
Metformin is a widely prescribed drug for the treatment of type 2 diabetes. Previous studies have de...
International audienceMetformin, a drug widely used in the treatment of Type II diabetes, has recent...
<p><b>A)</b> Mouse primary hepatocytes were cultured on permanox Lab-Tek 8-well chamber slides with ...
<p><b>A)</b> Effect of metformin on cellular ATP level. Mouse primary hepatocytes were treated with ...
Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of a...
<p>Outcome data from metformin-treated groups and control groups were extracted from primary studies...
Late-phase clinical trials investigating metformin as a cancer therapy are underway. However, there ...
Late-phase clinical trials investigating metformin as a cancer therapy are underway. However, there ...
<p>(<b>A</b>) Four human GB cell lines (U87, U251, LN18 and SF767) were treated with or without metf...
<p><b>A.</b> MCF7 cells were treated with metformin (8 mM) for 15 hours in either 25 mM or 2.5 mM gl...
<p>Histochemical analysis of muscle fibers stained for NADH transferase activity. Panels A to F show...
<p>A: Representative immunoblot analysis of cyclin D1, D2 and D3 in BPH-1 cells 48 hours after treat...
<p><b>(A-B)</b> 7721 and HepG2 cells were treated with metformin for different time points up to 96 ...
International audienceMetformin is a drug from the biguanide family that is used for decades as the ...
<p>Optical density was expressed as pTen, p53, cyclin D1, p21, Ras, Rb and E2F1 values normalized to...
Metformin is a widely prescribed drug for the treatment of type 2 diabetes. Previous studies have de...
International audienceMetformin, a drug widely used in the treatment of Type II diabetes, has recent...