Gene transcription analysis as determined by Affymetrix Gene Array Technology.

<p>The Venn diagrams presented show the number of transcriptomes expressed and overlaps in the kidneys of animals treated with valproic acid (VPA), dexamethasone (Dex) or untreated (None; Vehicle control) at 3, 24 and 120 hours (h) post ischemia-reperfusion (IR). All relative changes in gene expression are derived from comparison with naïve rats. Fewer genes were up-regulated in the VPA group compared to untreated Vehicle control group at 3 h post-IR. At 120 h post-IR only two genes were upregulated and none was downregulated in VPA treated animals. Specific gene expression information is presented in <b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126622#pone.0126622.s001" target="_blank">S1</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126622#pone.0126622.s006" target="_blank">S6</a> Tables</b>. The DNA microarray data have been deposited in NCBI’s Gene Expression Omnibus (GEO) repository and are accessible through Accession No. GSE58438 (<a href="http://www.ncbi.nlm.nih.gov/geo/" target="_blank">http://www.ncbi.nlm.nih.gov/geo/</a>).