55P0001 initially reduces, but later elevates blood glucose during a glucose tolerance test in mice.

<p>Male C57BL/6J mice were intraperitoneally injected with 10 mg/kg (left) or 50 mg/kg (right) 55P0001 (solid lines), or with the vehicle (broken lines) immediately before an oral glucose tolerance test (3 g/kg). The insert shows the chemical structure of 55P0001. Means±SEM; n = 11 each; *p<0.05, †p<0.001 vs. vehicle.