Intraplantar carrageenan injection increases Cav3.2 immunoreactivity in a subpopulation of ipsilateral L5 DRG neurons on Day 2 post-injection.

<p>(A-C) In saline-treated mice, representative immunostaining images showing Cav3.2 (A), TRPV1 (B), and both (C). Arrows indicate co-localization of Cav3.2-IR with TRPV1-IR. (D-F) In carrageenan-treated mice, representative immunostaining images showing Cav3.2 (D), TRPV1 (E), and both (F). Arrows indicate co-localization of Cav3.2-IR with TRPV1-IR. (G) The percentage of Cav3.2-immunoreactive cells relative to all L5 DRG neurons from mice treated with saline or carrageenan. (H) The percentage of Cav3.2-immunoreactive cells in TRPV1-positive neurons from mice treated with saline or carrageenan. (n = 3 mice for each group). *p < 0.05 compared with the saline control (unpaired Student's <i>t-test</i>).