Significantly differentially expressed miRNAs between mid- and late-gestational fetal KCs.

<p>(a) Eighty-eight known miRNAs that exhibited a change in expression of more than 2.0-fold in late-gestational fetal KCs. Fifteen of these were statistically up-regulated, and the others were statistically down-regulated. The read number of the miRNAs was normalized to the total number of high-quality reads that matched the human genome from each sample (12591141/12266070/12065253/12074661/13021411/12659579). MG represents mid-gestational, and LG represents late-gestational. The ratio represents the relative expression of miRNAs in late-gestational KCs. (b) Twenty-two novel miRNA candidates that exhibited a change in expression of more than 2.0-fold in late-gestational fetal KCs. Two of them were statistically up-regulated, and the others were statistically down-regulated. The read number of miRNAs was normalized to the total number of high-quality reads that matched the human genome from each sample (12591141/12266070/12065253/12074661/13021411/12659579). MG represents mid-gestational, and LG represents late-gestational. The ratio represents the relative expression of miRNAs in late-gestational KCs.