Comparison of amino acid positions related to antigenic variation of H1N1 seasonal influenza viruses identified by current and previous studies.

<p>^aTwenty-three antigenicity-associated sites identified by random forest regression.</p><p>^bTwenty antigenicity-associated sites identified by support vector regression based on recursive feature elimination.</p><p>^cForty-one natural epitope residues identified by Huang <i>et al</i>. [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126742#pone.0126742.ref013" target="_blank">13</a>].</p><p>^dFifteen cluster-difference substitutions revealed by antigenic cartography.</p><p>^eFive antigenic epitope regions described by Brownlee and Fodor [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0126742#pone.0126742.ref037" target="_blank">37</a>].</p><p>Comparison of amino acid positions related to antigenic variation of H1N1 seasonal influenza viruses identified by current and previous studies.