Nebulization with rh-TFPI does not influence local or systemic fibrinolysis.
- Florry E. van den Boogaard (740749)
- Jorrit J. Hofstra (284387)
- Cornelis van ‘t Veer (694059)
- Marcel M. Levi (263754)
- Joris J. T. H. Roelofs (116646)
- Tom van der Poll (33907)
- Marcus J. Schultz (116652)
Publication date
May 2015
DOIAbstract
<p>Plasminogen activator activity (PAA) and plasminogen activator inhibitor (PAI)-1 activity in BALF (A and B) and PAA in plasma (C) in rats nebulized with rh-TFPI (SP rh-TFPI, open bars) or vehicle (SP control, black bars) 42 hours after intratracheal instillation of <i>S</i>. <i>pneumoniae</i> and in naïve control rats (control, grey bars). Bars depict median ± IQR; ##p < 0.01 versus naïve controls.</p
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