Myriocin reduces hepatic and plasma ceramides and sphingomyelin (SM) in LDLR<sup>-/-</sup> mice (mean±SD, n = 6).
- Takhar Kasumov (741675)
- Ling Li (38566)
- Min Li (12799)
- Kailash Gulshan (741676)
- John P. Kirwan (741677)
- Xiuli Liu (741678)
- Stephen Previs (741679)
- Belinda Willard (129588)
- Jonathan D. Smith (38004)
- Arthur McCullough (741680)
Publication date
May 2015
DOIAbstract
<p>Distribution of ceramide species in the liver (<b>A</b>). Total amount of ceramides in the liver (<b>B</b>). Distribution of ceramide species in plasma (<b>C</b>). Total ceramides in plasma (<b>D</b>), Hepatic (<b>E</b>) and Plasma (<b>F</b>) levels of SM. *<i>P</i><0.001, compared to the SD and WD + myriocin groups. **<i>P</i><0.01, compared to the WD group.</p
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