K-means cluster analysis identifies 88 genes acutely upregulated in response to lesioning.
- Nicholas M. Kanaan (707720)
- Timothy J. Collier (741973)
- Allyson Cole-Strauss (741974)
- Tessa Grabinski (741975)
- Zachary R. Mattingly (741976)
- Mary E. Winn (176332)
- Kathy Steece-Collier (741977)
- Caryl E. Sortwell (490355)
- Fredric P. Manfredsson (490349)
- Jack W. Lipton (741978)
Publication date
May 2015
DOIAbstract
<p>Eight clusters were identified through consensus clustering analysis. We hypothesized that a cluster of genes would be highly upregulated due to 6-OHDA administration that would fall-off over time due to ongoing DA neuron degeneration. Cluster-1 followed this hypothesized pattern.</p
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