K8^+/- mice have increased crypt length.

<p>A. The K8^<b>+/-</b> baseline morphology was studied by H&E staining of the distal colon (DC) and proximal colon (PC) and the crypt lengths were measured (black arrows). B. Crypt lengths in PC and DC were measured from digital photographs of H&E stained colon sections (n = 3) taken with Zeiss Axiovert 200M microscope and processed using ImageJ software. The crypt lengths are expressed as mean length ± SD, calculated based on crypts from 3 animals / genotype.