<p><b>(A)</b> Chemical structure of EB. <b>(B)</b> HepG2/STAT3-luceferase reporter cells were pretreated with EB at indicated concentrations for 2 h, and luciferase activity was measured following stimulation with IL-6 (50 ng/ml) for 5 h. Data are expressed as mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001 versus the control group without EB but with IL-6 stimulation. <b>(C)</b> A549 cells were pretreated with EB at indicated concentrations for 2 h before stimulation by IL-6 (10 ng/ml) for 15 min. Whole cell lysates were processed for western blot analysis with the indicated antibodies. <b>(D)</b> A549 cells were pretreated with 20 μM EB for various time periods (0–120 min) before stimulation by IL-6 for 15 min. Whole cell lysates were p...
(A) The IL6 inhibitory antibody (0.15 μg/mL) prevented the autocrine activation of p-STAT3 upon addi...
<p>(A) Luciferase activity expressed by TCA8113 and 293T cells after transfection with the potential...
<p>(A) The expression of IL-6R in EBV-infected and uninfected NP460hTert cells was analyzed by Weste...
<p><b>(A)</b> MDA-MB-468, A549, MDA-MB-453 cells (3.0*10<sup>5</sup> per well) were treated with EB ...
<p><b>(A)</b> A549 cells were pretreated with DTT (0.5 mM), GSH (2 mM), EB (20 μM) or their mixture ...
<p><b>(A)</b> A549 cells were stimulated by IL-6 (10 ng/ml) for 15 min. The media were then replaced...
<p>A–D, MLE12 cells were transfected with indicated plasmids. 24 h later, cells were treated with or...
<p>MLE12 cells were treated with 20 ng/ml IL-1β for different time periods. A, the nuclear proteins ...
<div><p>(A) Western blot of total protein extracts (100 μg) from EBV-transformed B cells derived fro...
<p>(A) A schematic diagram showing the positive feedback loop of IL-6 activation of STAT3 and LMP1 e...
<p>(A) Primary B cells were infected with EBV and cultured for 72 hours, then resveratrol was added ...
<p>(A, B) TRAF6 represses the activity of STAT3 with IFNα stimulation. HEK293 cells were transiently...
<p>To confirm whether there is a physical interaction between STAT3 and ERα, we transfected 293T cel...
<p>A, MLE12 cells were transfected with 40 nM control siRNA or C/EBPβ-specific siRNA. 24 h later, RN...
<p><b>A.</b> ECs subjected to IL-6 (10ng/ml) treatment for 10 min were pretreated with or without 0....
(A) The IL6 inhibitory antibody (0.15 μg/mL) prevented the autocrine activation of p-STAT3 upon addi...
<p>(A) Luciferase activity expressed by TCA8113 and 293T cells after transfection with the potential...
<p>(A) The expression of IL-6R in EBV-infected and uninfected NP460hTert cells was analyzed by Weste...
<p><b>(A)</b> MDA-MB-468, A549, MDA-MB-453 cells (3.0*10<sup>5</sup> per well) were treated with EB ...
<p><b>(A)</b> A549 cells were pretreated with DTT (0.5 mM), GSH (2 mM), EB (20 μM) or their mixture ...
<p><b>(A)</b> A549 cells were stimulated by IL-6 (10 ng/ml) for 15 min. The media were then replaced...
<p>A–D, MLE12 cells were transfected with indicated plasmids. 24 h later, cells were treated with or...
<p>MLE12 cells were treated with 20 ng/ml IL-1β for different time periods. A, the nuclear proteins ...
<div><p>(A) Western blot of total protein extracts (100 μg) from EBV-transformed B cells derived fro...
<p>(A) A schematic diagram showing the positive feedback loop of IL-6 activation of STAT3 and LMP1 e...
<p>(A) Primary B cells were infected with EBV and cultured for 72 hours, then resveratrol was added ...
<p>(A, B) TRAF6 represses the activity of STAT3 with IFNα stimulation. HEK293 cells were transiently...
<p>To confirm whether there is a physical interaction between STAT3 and ERα, we transfected 293T cel...
<p>A, MLE12 cells were transfected with 40 nM control siRNA or C/EBPβ-specific siRNA. 24 h later, RN...
<p><b>A.</b> ECs subjected to IL-6 (10ng/ml) treatment for 10 min were pretreated with or without 0....
(A) The IL6 inhibitory antibody (0.15 μg/mL) prevented the autocrine activation of p-STAT3 upon addi...
<p>(A) Luciferase activity expressed by TCA8113 and 293T cells after transfection with the potential...
<p>(A) The expression of IL-6R in EBV-infected and uninfected NP460hTert cells was analyzed by Weste...