Cell and cytokine profile of neutrophil-high (Neu-High) asthma and neutrophil-normal (Neu-Normal) asthma.

<p>The upper limit of percent of neutrophils in the BAL fluid of healthy subjects was 2.4%. We separated all subjects with asthma into neutrophil-high (neutrophils% > 2.4%), and neutrophil-normal (neutrophil≤2.4%) groups. Compared to Neu-Normal asthma, Neu-High asthma had higher IL-8 levels (p<0.01) and lower % predicted FEV₁ (p<0.01), but similar levels of eosinophil %, IL-5, IL-13, IL-16, and PDGF-bb. Data are expressed as means ± SEM. *<i>P</i> < .05, **<i>P</i> < .01.