<p>WGCNA analysis identified six gene networks which were dysregulated between <i>C9ORF72</i>-ALS and control samples. The median fold change of genes within each network and the functional enrichment of each of the gene networks is tabulated. A fold change of >1 equates to up-regulation and a fold change of <1 equates to down-regulation.</p><p>Gene level network analysis of transcriptome changes in motor neurons from <i>C9ORF72</i>-ALS cases.</p
Objective An intronic GGGGCC-repeat expansion of C9ORF72 is the most common genetic variant of amyot...
Recent evidence suggested that muscle degeneration might lead and/or contribute to neurodegeneration...
Background: The pathogenesis of Alzheimer's disease is associated with dysregulation at different le...
<p>WGCNA analysis identified six gene networks which were dysregulated between <i>C9ORF72</i>-ALS an...
<p>WGCNA analysis identified nine gene networks which were dysregulated between C9ORF72-ALS and cont...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of motor neurons resulting in pro...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease defined by motor neuron (MN) loss...
Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a lethal disorder characterized by progre...
Altres ajuts: PERIS program SLT006/17/125 to D.A.To identify transcriptomic changes, neuropathologic...
The aim of the present study is to investigate the molecular pathways underlying amyotrophic lateral...
Amyotrophic lateral sclerosis (ALS) is a fatal late-onset motor neuron disease characterized by the ...
Recent evidence suggested that muscle degeneration might lead and/or contribute to neurodegeneration...
Neurodegenerative diseases are challenging for systems biology because of the lack of reliable anima...
ALS is a devastating neurodegenerative disorder with no known cure. In this thesis, I describe high-...
Summary: Neurodegenerative diseases are challenging for systems biology because of the lack of relia...
Objective An intronic GGGGCC-repeat expansion of C9ORF72 is the most common genetic variant of amyot...
Recent evidence suggested that muscle degeneration might lead and/or contribute to neurodegeneration...
Background: The pathogenesis of Alzheimer's disease is associated with dysregulation at different le...
<p>WGCNA analysis identified six gene networks which were dysregulated between <i>C9ORF72</i>-ALS an...
<p>WGCNA analysis identified nine gene networks which were dysregulated between C9ORF72-ALS and cont...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of motor neurons resulting in pro...
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease defined by motor neuron (MN) loss...
Abstract Background Amyotrophic Lateral Sclerosis (ALS) is a lethal disorder characterized by progre...
Altres ajuts: PERIS program SLT006/17/125 to D.A.To identify transcriptomic changes, neuropathologic...
The aim of the present study is to investigate the molecular pathways underlying amyotrophic lateral...
Amyotrophic lateral sclerosis (ALS) is a fatal late-onset motor neuron disease characterized by the ...
Recent evidence suggested that muscle degeneration might lead and/or contribute to neurodegeneration...
Neurodegenerative diseases are challenging for systems biology because of the lack of reliable anima...
ALS is a devastating neurodegenerative disorder with no known cure. In this thesis, I describe high-...
Summary: Neurodegenerative diseases are challenging for systems biology because of the lack of relia...
Objective An intronic GGGGCC-repeat expansion of C9ORF72 is the most common genetic variant of amyot...
Recent evidence suggested that muscle degeneration might lead and/or contribute to neurodegeneration...
Background: The pathogenesis of Alzheimer's disease is associated with dysregulation at different le...