The simvastatin on plasma creatine kinase (CK) activity and total cholesterol.

<p>Rats were treated with vehicle (Control) or simvastatin at 60 (Sim 60) and 80 mg.kg^-1.day^-1 (Sim 80) for 14 days. (<b>A</b>) Plasma CK activity. (<b>B</b>) Plasma [total cholesterol]. *—significantly different from Control and Sim 60 groups. Mean ± SEM. n = 8/group. One way ANOVA with Newman-Keul’s post-hoc test. P < 0.05.