Vascular collagen fiber deposition.

<p>Picrosirius red-stained sections assessed by bright field (A, C, E—left column) and polarized light (B, D, E—right column), indicate perivascular fibrosis in carotid arteries. The polarized light showed an important deposition of thin, young collagen fibers (green), a relative low deposition of mature (thick, red) and intermediary (yellow) collagen fibers in control group. On the other hand, salt2 group showed a significant reduction of thin fibers and increase of intermediary and thick collagen fibers. Salt12 group showed a pattern similar to the control group. (Magnification 1000x. Groups: Control, A-B; Salt2, C-D; Salt12, E-F. White arrow: thin fiber; Yellow arrow: thick fibers).