Association between change in fitness (VO_2peak) and change in HRQoL, regardless of study group.

<p>PCS: Physical Component Score (1–5). MCS: Mental Component Score (4–8).</p><p>*Crude model 1 = (Fitness at 16 weeks minus Fitness at baseline) = independent, (SF-36 Score at 16 weeks minus SF-36 Score at baseline) = dependent.</p><p>†Adjusted model 2 = model 1 adjusted for intervention group, age, education, baseline SF-36 score and baseline VO_2peak (per 10 mL/min)</p><p>‡Adjusted model 3 = model 1 adjusted for intervention group, age, education, baseline SF-36 score, baseline VO_2peak (per 10 mL/min) and change in weight.</p><p>§St-b (with 95% confidence interval, 95%CI) is the regression coefficient from linear regression models that represents the number of standard deviations (SD) change in HRQoL (dependent variable), per 1 SD change in fitness VO_2peak, per 10 mL/min, independent variable). E.g., an St-b of 0.16 means that if fitness increases by 1 SD, the mean SF-36 domain score increases by 0.16 SD.</p><p>Association between change in fitness (VO_2peak) and change in HRQoL, regardless of study group.