<p>TCC = tumor cell content (%); VF = variant frequency; AR = amplicon reads</p><p>*: variant observed with the old library with the same panel for the same DNA sample</p><p>**: low coverage / high frequency variants that were initially missed with the 125 coverage cut-off.</p><p>Comparison of genotypes for amino acid changing variants in paired panel and sample series.</p
<p>Sequence variants key marks reveal by experimental, statistic and <i>in silico</i> analysis. A de...
<p><b>Comparison of variant detection (shown as values of variant allelic fraction; AF) in DNA refer...
#<p>significantly different p<0.01 - z-test.</p><p>Haplotype distribution and somatic polymorphism r...
The 1000 Genomes Project data provides a natural background dataset for amino acid germline mutation...
<div><p>The 1000 Genomes Project data provides a natural background dataset for amino acid germline ...
BackgroundTumor mutation burden (TMB) is a biomarker frequently reported by clinical laboratories, w...
<p>Genes containing variants were identified with the <i>disease association panel</i> (<b>A-C</b>) ...
<p><b>A</b>. Scatter plot for all 84,861 variants that occur both in the NCI-60 and the ESP5400. The...
<p><b>A.</b> Comparison of the B and T panels with respect to amplicon targets. Common amplicons had...
<p>Abbreviations: NT, nucleotide change in NM_017757; AA, amino acid change in NP_060227; Pred, Poly...
Quantification of tumor‐specific variants (TSVs) in cell‐free DNA is rapidly evolving as a prognosti...
<p>N: number; group 4: same DNA sample, different panels; group 5: same panel & tumor, different DNA...
Sequence variants (SV) are protein products that contain unintended substitutions in the amino acid ...
<p>Five cases with matched tumor—blood samples are shown. Annotations in black letters are given for...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>Sequence variants key marks reveal by experimental, statistic and <i>in silico</i> analysis. A de...
<p><b>Comparison of variant detection (shown as values of variant allelic fraction; AF) in DNA refer...
#<p>significantly different p<0.01 - z-test.</p><p>Haplotype distribution and somatic polymorphism r...
The 1000 Genomes Project data provides a natural background dataset for amino acid germline mutation...
<div><p>The 1000 Genomes Project data provides a natural background dataset for amino acid germline ...
BackgroundTumor mutation burden (TMB) is a biomarker frequently reported by clinical laboratories, w...
<p>Genes containing variants were identified with the <i>disease association panel</i> (<b>A-C</b>) ...
<p><b>A</b>. Scatter plot for all 84,861 variants that occur both in the NCI-60 and the ESP5400. The...
<p><b>A.</b> Comparison of the B and T panels with respect to amplicon targets. Common amplicons had...
<p>Abbreviations: NT, nucleotide change in NM_017757; AA, amino acid change in NP_060227; Pred, Poly...
Quantification of tumor‐specific variants (TSVs) in cell‐free DNA is rapidly evolving as a prognosti...
<p>N: number; group 4: same DNA sample, different panels; group 5: same panel & tumor, different DNA...
Sequence variants (SV) are protein products that contain unintended substitutions in the amino acid ...
<p>Five cases with matched tumor—blood samples are shown. Annotations in black letters are given for...
<p><b>A</b>–<b>B</b>. Comparison of the variant allelic frequency of mutations detected using whole ...
<p>Sequence variants key marks reveal by experimental, statistic and <i>in silico</i> analysis. A de...
<p><b>Comparison of variant detection (shown as values of variant allelic fraction; AF) in DNA refer...
#<p>significantly different p<0.01 - z-test.</p><p>Haplotype distribution and somatic polymorphism r...