Brain activation differences to the actual trial (NS > NN).

<p>Patients with social anxiety disorder (SAD) display an enhanced activation in the left amygdala (a), right (b) and left insula (c), medial prefrontal cortex [mPFC; (d)], dorsal anterior cingulate cortex [ACC; (e)], and left opercular inferior frontal gyrus [IFG; (f)] as compared to healthy control subjects (HC). Statistical parametric maps are overlaid on an averaged T1 scan (radiological convention: left = right). The plots at the right side display contrasts of parameter estimates (mean ± standard error for maximally activated voxel).