<p>Time to footpad swelling (or ectopic lesions) in mice treated with either RIF+STR (green circles), RIF+CLR (blue triangles), or RIF+CFZ (red circles) regimens for six weeks (A) or eight (B) weeks after the development of swollen foot pads. Footpads had little or no swelling at treatment completion (see <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0003823#pntd.0003823.g001" target="_blank">Fig 1A</a>).</p
<p>Decrease in the log<sub>10</sub> CFU counts in the footpads of mice treated with, streptomycin+ r...
<p>Mice were infected with <i>M. ulcerans</i> strain 98–912 and were left untreated (closed circles)...
<p>Due to animal welfare reasons, mice were sacrificed early as explained in text.</p><p>D, day; w, ...
<p>After infection in the right hind footpad (RHFP), grade 1 swelling was first detected at 5 weeks....
<p>Kaplan-Meier curve depicting the percentage of mice free of footpad swelling during 39 weeks of f...
<p><b>(A) Footpad swelling</b>. After infection of both hind footpads, treatment began when swelling...
<p>After infection in the right hind footpad (RHFP), there were increases in the numbers of <i>M. ul...
BALB/c mice were inoculated in their footpad with L. major. After 21 days, mice were treated i.p. wi...
<p>The number in parenthesis indicates the number of mice kept for footpad swelling.</p><p>D-25 is t...
<p>Mice were monitored weekly for renewed swelling of infected footpads after treatment completion. ...
<p>Mice were randomized after infection with 0.03 ml of an inoculum containing 6.06 log<sub>10</sub>...
<p>Mean CFU count from mouse footpads on the day after infection (Day1), the day of treatment initia...
<p>Mice were either non-immunized (•) or immunized with BCG (○) two months before challenge. All mic...
<p>BALB/c mice (five per group) were immunized twice with DNA antigens and controls in the presence ...
<p>Schematic presentation of the mean footpad measurements via caliper based method in mm (left axis...
<p>Decrease in the log<sub>10</sub> CFU counts in the footpads of mice treated with, streptomycin+ r...
<p>Mice were infected with <i>M. ulcerans</i> strain 98–912 and were left untreated (closed circles)...
<p>Due to animal welfare reasons, mice were sacrificed early as explained in text.</p><p>D, day; w, ...
<p>After infection in the right hind footpad (RHFP), grade 1 swelling was first detected at 5 weeks....
<p>Kaplan-Meier curve depicting the percentage of mice free of footpad swelling during 39 weeks of f...
<p><b>(A) Footpad swelling</b>. After infection of both hind footpads, treatment began when swelling...
<p>After infection in the right hind footpad (RHFP), there were increases in the numbers of <i>M. ul...
BALB/c mice were inoculated in their footpad with L. major. After 21 days, mice were treated i.p. wi...
<p>The number in parenthesis indicates the number of mice kept for footpad swelling.</p><p>D-25 is t...
<p>Mice were monitored weekly for renewed swelling of infected footpads after treatment completion. ...
<p>Mice were randomized after infection with 0.03 ml of an inoculum containing 6.06 log<sub>10</sub>...
<p>Mean CFU count from mouse footpads on the day after infection (Day1), the day of treatment initia...
<p>Mice were either non-immunized (•) or immunized with BCG (○) two months before challenge. All mic...
<p>BALB/c mice (five per group) were immunized twice with DNA antigens and controls in the presence ...
<p>Schematic presentation of the mean footpad measurements via caliper based method in mm (left axis...
<p>Decrease in the log<sub>10</sub> CFU counts in the footpads of mice treated with, streptomycin+ r...
<p>Mice were infected with <i>M. ulcerans</i> strain 98–912 and were left untreated (closed circles)...
<p>Due to animal welfare reasons, mice were sacrificed early as explained in text.</p><p>D, day; w, ...